It’s well established in the field of immuno-oncology that in
nearly all cancers, a subset of patients presents with an immune infiltrate. In
many of these tumors, the infiltrating immune cells appear to form aggregates
that are especially noticeable at the tumor periphery. Indeed, when presenting
my research on these aggregates at scientific meetings, I’ve often been
approached by other scientists or clinicians who indicate that they’ve seen
lymphoid aggregates in tumor tissue from their patients, but didn’t know to
investigate them further.
This brief overview may change some of those minds.