The Sentinel

THE OFFICIAL BLOG OF THE SOCIETY FOR IMMUNOTHERAPY OF CANCER (SITC).

Showing posts with label ACI. Show all posts
Showing posts with label ACI. Show all posts

Tuesday, January 7, 2020

President's Message - January 2020

Dear Colleagues,

In my December President’s Message, I outlined our society’s future ambitions, focused on six strategic goals through 2021. This month, I’d like to describe some of the programs and initiatives to achieve those strategic goals.

SITC strives to be the most comprehensive and reliable resource for information and education on cancer immunotherapy. One way in which our society serves the greater cancer immunotherapy field is through our open access, peer-reviewed Journal for ImmunoTherapy of Cancer (JITC). The quality of research presented in the journal has grown over the years and it is now arguably the top journal focusing on cancer immunotherapy. Given this growth, SITC officially transitioned JITC to a new publisher this month, BMJ, giving JITC the optimal platform to engage readers, authors and the greater field of tumor immunology and cancer immunotherapy. Learn more in this special editorial from JITC Editor-in-Chief Pedro J. Romero, MD.

SITC is invested in developing the next generation of leaders in tumor immunology and cancer immunotherapy. To further this mission, we will offer five SITC Fellowship Awards in 2020, providing a total of a half-million dollars in funding opportunities to promising young investigators. The submission period for these funding and award opportunities is Jan. 21–March 2, 2020. Thank you to our industry partners who help make these annual award opportunities possible as we work together to develop the future leaders in the field.

The Women in Cancer Immunotherapy Network (WIN) Leadership Institute is another successful leadership development program that will grow in 2020. The 2019 WIN Leadership Institute held this past August hosted more than 60 emerging female leaders in the field. Because of the strong interest and demand for this program, and the overwhelming positive response to the first program, SITC will host two such events in 2020. I’m proud of SITC commitment to the professional development of women in the field, and I thank Immediate Past President Lisa H. Butterfield, PhD, for her role as a champion for the WIN initiative.

SITC’s main goal of improving cancer care and patient outcomes is reliant upon the commitment of time and expertise from our members from around the globe. The SITC Cancer Immunotherapy Guidelines are consensus-based clinical practice guidelines, developed by panels of experts, that help inform oncologists on when and how to use immunotherapy and how to manage the associated toxicities. SITC has now published seven different guidelines, including the recently updated consensus statement on renal cell carcinoma (RCC), which appeared in JITC in December. Five additional guidelines are currently under development and scheduled for publication in 2020.

Don’t forget to register for the free SITC webinar focused on the recently published RCC manuscript. Beginning at 11 a.m. EST on Tuesday, Jan. 7, this webinar will include an overview of the manuscript, and will review management of immune-related adverse events. Faculty will also be available for a Q&A session.

Also, please consider attending other SITC programs quickly approaching, including the Cancer Immunotherapy Winter School (Jan. 13–17 in Houston; onsite registration is available) and the Interrogating the Tumor-Specific Surfaceome for Immune Targeting workshop (April 23–24 in San Diego). Additionally, online registration is open for our upcoming Advances in Cancer Immunotherapy™ regional education programs in Charlotte, N.C., on Jan. 23, in Charleston, S.C., on Feb. 1, in Tucson, Ariz., on March 14, in Tampa, Fla., on March 21 and Seattle on March 28.

There are many other programs, initiatives, educational resources and more that SITC has planned in 2020 (here's a preview). I look forward to an exciting year ahead for our society and our members, and I hope to see you in a future SITC program in 2020.

Sincerely,















Mario Sznol, MD
SITC President

Monday, September 16, 2019

President's Message - September 2019

Dear Colleagues,

I’d like to begin this month’s President’s Message honoring Stan Collender (1951-2019). Stan, an immunotherapy pioneer and advocate, was a cancer patient of past SITC President Michael B. Atkins, MD. Dr. Atkins first met Stan in 2012 when he presented with Merkel Cell Carcinoma. From there, they developed a close relationship as Stan courageously fought his disease with immunotherapy for many years. Their experience and efforts together taught us much about the impact and limitations of immunotherapy. Read more about Stan’s life and contributions to our field in the heartfelt memorial posted by Dr. Atkins to The Sentinel, SITC’s official blog.

As you know, breakthroughs in research and the advent of new cancer immunotherapy treatments this century spurred an explosion of interest and investment in our field. Through offerings like the Annual Meeting & Pre-Conference Programs, the Society for Immunotherapy of Cancer (SITC) brings together the most accomplished and innovative researchers in the field to spark new collaborations and force consideration of new ideas that prompt discovery of new targets and approaches.

While the SITC Annual Meeting is perhaps our most important and visible effort to advance science and improve patient outcomes, many other SITC activities contribute to our core mission. SITC’s Advances in Cancer Immunotherapy™ (ACI) regional education series is an example of how SITC leverages its member’s clinical and science expertise to inform patient care, particularly safe and effective treatment administration. At the other end of the spectrum of SITC programs, the society seeks to expand research and knowledge in our field through the professional development of early career scientists. Young investigators are the future of cancer immunotherapy research. SITC is investing in their future through a variety of programs that provide education and professional development and promote community and collaboration.

One of our most effective programs aimed at young investigators is the SITC Meet-the-Experts – an annual luncheon at the SITC Annual Meeting (Thursday, Nov. 7, 2019, at 12:05 p.m.) organized by the Early Career Scientist Committee that connects young investigators with leaders in the field. It has now grown to a year-round initiative featuring regular, free webinars. These online events focus on various topics that are pertinent to an early career scientist’s professional development. Most recently, Tullia Bruno, PhD (University of Pittsburgh), moderated our Aug. 22 webinar focused on Careers in Science Away from the Bench, which you can view on-demand here.

SITC will once again host a Cancer Immunotherapy Winter School on Jan. 13-17, 2020, at the Hilton Houston Post Oak in Houston, Texas. Led by program organizers Lisa H. Butterfield, PhD (Parker Institute for Cancer Immunotherapy/University of California San Francisco), and Leisha A. Emens, MD, PhD (UPMC Hillman Cancer Center), this program provides intensive instruction on the core principles of tumor immunology and cancer immunotherapy. These programs also foster connections among peers which is critical component to their future success.

SITC also strengthens the support network for young scientists through the Professional Interest Communities. These digital discussion forums connect individuals of similar professional and personal backgrounds to share career development needs, address professional hurdles and more.

Beyond the basic education and professional development offered by SITC, SITC Fellowships provide funding to support the early careers of the most talented scientists. Supported through the Forward Fund, SITC has awarded more than $2 million in Fellowship Awards since 2014. Stay tuned later this year for information about 2020 SITC Fellowships.

SITC offers an affordable membership rate of $50 for students and scientists-in-training. Joining our society provides discounted access to vital SITC in-person programs and reduced fees on articles accepted to the Journal for ImmunoTherapy of Cancer (JITC). It also places young investigators in a professional network of the most influential basic scientists, translational researchers and clinicians in the field. Click here to become a SITC member and join the world’s leading organization dedicated solely to cancer immunotherapy research.

Finally, I would like to recognize and thank the countless number of women who organized, facilitated and attended SITC’s Women in Cancer Immunotherapy Network Leadership Institute in Seattle last month. This exciting new program from SITC, championed by immediate Past President Lisa H. Butterfield, PhD, was a rousing success. I look forward to seeing our society continue its effort to support, advance and celebrate the success of women in our field.

Sincerely,















Mario Sznol, MD
SITC President

Tuesday, August 6, 2019

President's Message - August 2019

Dear Colleagues,

Since its creation in 1984, the Society for Immunotherapy of Cancer (SITC) has steadfastly pursued its goals to advance the science and application of tumor immunology and cancer immunotherapy. As the U.S. Food and Drug Administration, and other authorities around the world, have approved use of numerous immunotherapy treatments in recent years for a variety of cancers, education of the patient care team has become one of the most critical initiatives of our society.

To achieve its educational goals, SITC and its members have developed state-of-the-art programs, both online and in-person. An example of online resources is the SITC library of Cancer Immunotherapy Guidelines. The most recent publication in this series contains clinical treatment recommendations for clinicians administering immunotherapy for patients with HNSCC and is published in the Journal for ImmunoTherapy of Cancer (JITC) – our open access, peer-reviewed online journal. Congratulations to the SITC Cancer Immunotherapy Guidelines Head and Neck Subcommittee for authoring this important consensus statement.

For in-person education, the Advances in Cancer Immunotherapy™ (ACI) regional programs have been particularly effective and popular. Approaching its seventh year, ACIs are held in 15 communities around North America each year, and include national and local experts on cancer immunotherapy across the disease spectrum. SITC will again offer the program free of charge for healthcare professionals in the clinical setting, students and patient advocates ACI programs provide:

  • In-depth information on treating patients with FDA-approved immunotherapies
  • Analysis and interpretation of new clinical data supporting the use of checkpoint inhibitors, CAR T therapies, cytokines, oncolytic viruses and vaccines
  • Education enabling clinicians and other health care personnel to more effectively identify and manage immune-related adverse events
  • Strategies to overcome operational and reimbursement barriers to incorporating immunotherapy into practice

I’ve served as an ACI faculty member myself, and seen first-hand SITC’s ability to draw from a vast network of scientific and clinical experts to provide an outstanding educational program. Attendees acquire a better understanding of current practices and known challenges to administering cancer immunotherapy treatments. All ACIs are CME-, CNE-, CPE- and MOC-certified, assisting clinicians in providing state of the art care to their patients.

Beginning in September and through March 2020, SITC will bring its ACI program to 15 cities around North America. Registration is currently open for Cleveland (Sept. 5), Chicago (Sept. 28), Boston (Oct. 10), Buffalo, N.Y. (Oct. 26) and Nashville, Tenn. (Dec. 4). Remaining cities that will host an ACI in the coming year include: Philadelphia; San Francisco; Birmingham, Ala.; Charlotte, N.C.; San Diego; Washington, D.C.; Tampa, Fla.; Tucson, Ariz.; Vancouver, British Columbia, Canada; and San Antonio. Stay tuned to the SITC website for dates and registration information on upcoming ACIs.

Finally, I’d like to share a quick reminder that we are nearly a month out from SITC’s upcoming interim workshops on cancer immune responsiveness (Sept. 4-5) and adoptive cellular therapies (Sept. 5-6) in Houston. The deadline to save money on housing is Wednesday, Aug. 14, with online registration closing Wednesday, Aug. 28, so don’t hesitate in securing your spot for these engaging scientific and clinical workshops. I hope to see you in Texas!

Sincerely,















Mario Sznol, MD
SITC President