The Sentinel

THE OFFICIAL BLOG OF THE SOCIETY FOR IMMUNOTHERAPY OF CANCER (SITC).

Showing posts with label SITC Sparkathon. Show all posts
Showing posts with label SITC Sparkathon. Show all posts

Thursday, May 31, 2018

President's Message – June 2018


Dear Colleagues,

As summer begins, I am happy to share news about a number of SITC initiatives that our members are involved in, addressing important aspects of our field.

First, I would like to congratulate members of the SITC Immunoscore Validation Project – whose Steering Committee is Chaired by Past SITC President Bernard A. Fox, PhD – on the recent publication of its study's findings in The Lancet. Involving tissues banked from more than 3,500 patients and more than a dozen SITC member volunteers across 13 countries, the study showed that the Immunoscore measures of stage I-III colon cancer patients positively correlated with survival and time to recurrence. I highly recommend that you read this important publication.

Second, I would like to commend the work of the SITC Cancer Immune Responsiveness Task Force and Immune Biomarkers Committee for their effort in hosting a pair of SITC workshops earlier this month in San Francisco. More than 200 attendees contributed to discussion around the current major questions in our field which will lead directly to new initiatives for the society in these areas. Attendees also developed new collaborations to move the field forward. Stay tuned as these new initiatives are announced, and materials from these workshops become available to members and the general public later this month.

Third, I want to share the news that our highly anticipated Cancer Immunotherapy Guidelines for cutaneous melanoma update published on Wednesday! First published in 2013, these clinical guidelines serve to educate a clinical audience on a disease state that was among the first to achieve significant progress via cancer immunotherapy for patients. Thank you to the Cancer Immunotherapy Guidelines Cutaneous Melanoma Subcommittee for your major commitment to this effort! This melanoma manuscript is the first in our society's series of Cancer Immunotherapy Guidelines to receive an update. New guidelines in non-small cell lung cancer and head and neck cancers will publish this year in our society's Journal for ImmunoTherapy of Cancer (JITC).

Another way that SITC seeks to improve our field's future is through the SITC Sparkathon. Young investigators can apply now to participate in the SITC Sparkathon Class of 2018. This team science opportunity, which will last 12-18 months, forges new collaborations among the field's brightest early career scientists as they seek to solve an existing obstacle. These scientists will receive valuable professional development from top business coaches and SITC leadership. Applications are due by 11:59 p.m. EDT on Monday, June 18.

The inaugural SITC Sparkathon Class of 2017, teams TimIOs and METIOR Incubator, will present their projects during the 33rd Annual Meeting this November.

Very soon, our society members will elect a new Vice President in the upcoming annual election. From June 14–28, the 2018 SITC Election will include the Vice President position and three At-Large Director openings on the Board of Directors. Learn more about this year's candidates, who are also listed below, and please remember to vote (online voting begins June 14).

Finally, I am happy to share that current registration numbers confirm our expectations that SITC 2018 will be our society's most highly attended yet! Register now to attend SITC 2018 and secure your housing. Also, don't forget the deadline to submit regular abstracts, late-breaking abstract applications or applications to the Immune Escape program is 5 p.m. PDT on Aug. 1.

I'm looking forward to seeing you all at the Walter E. Washington Convention Center in Washington, D.C. this November!

Sincerely,













Lisa H. Butterfield, PhD
SITC President

Tuesday, May 15, 2018

The METIOR Incubator and Educating the Next Generation of Immuno-Oncology Experts

by Saman Maleki, PhD

In August 2017, SITC brought together a group of 29 young researchers and physicians, from across the world, that were involved in various aspects of immunotherapy research to compete in a bold new program called “Sparkathon.” These people were divided into three teams and tasked to work together to develop a solution tackling the most pressing hurdles facing the fast-growing field of cancer immunotherapy. Each team was assigned a mentor with extensive science and business background and teams formulated their solutions to a business deck and pitched it to a group of SITC leaders, academics, and industry experts.

One of the teams set to address the educational challenge facing early-career researchers ­– from any background/sector – who want to enter the field of Immuno-Oncology. This novel educational program is named Mentoring for Early Translational Immuno-Oncology Researchers (METIOR) incubator. It brings together researchers from various sectors and backgrounds and educates them about Immuno-Oncology while developing a team-based multi-institutional project under the mentorship of immunotherapy experts from academia and industry. The METIOR incubator received $75,000 in seed funding from SITC to assist the establishment of their unique educational program. 

METIOR incubator selected ten participants from a pool of highly qualified applicants with various backgrounds in cancer research and assigned them into two teams: 1) team Checkpoints and 2) team CAR T-cell. Each team is currently working on two different projects that is directly linked to cancer immunotherapy. Participants met each other and their mentors at the first METIOR retreat at The University of Pennsylvania (Philadelphia) in March 2018. After two intense days of mentored brainstorming and project development, each team received $20,000 in seed money to work on their respective projects.

Team checkpoint seeks to identify biomarkers that are associated with the activity of endogenous retroviruses with double-stranded RNAs (dsRNAs) in ovarian cancer that might sensitize these tumors to checkpoint inhibitors.

Team CAR T-cell aims to build a centralized information platform (Virtual Immune-oncology Tissue Consortium, VITC) comprising of reference to clinical and pre-clinical samples with a focus on immunotherapy. This platform will be the first of its kind to efficiently consolidate immunotherapy resources across institutions into a searchable, interactive scientific network accessible to all researchers worldwide.

Teams have monthly teleconference meeting with their mentors and will meet again, in person, with their mentors in early September in London, Ontario for the second METIOR Incubator retreat. They will work on consolidating their ideas and preliminary results to shape a joint grant application with the goal of seeking major peer-reviewed funding. The last METIOR Incubator retreat would be at the SITC 33rd Annual Meeting in Washington, D.C. in November, where each team will present their progresses during the noon hour on Friday (TimIOs) and Saturday (METIOR). For a complete look at the Annual Meet schedule, click here.





Acknowledgment:
Author wished to thank Ms. Alexandra Cadena and Dr. Sebastiano Battaglia for their proofreading of this article.

Thursday, June 29, 2017

President's Message - June 2017

Dear Colleagues,

As those who attended the American Society of Clinical Oncology’s (ASCO) 2017 Annual Meeting earlier this month can attest, the field of cancer immunotherapy continues to explode, with more than 80 immunotherapy educational sessions and abstract presentations over five days, and many poster presentations. Cancer immunotherapy has emerged as a clinically beneficial option for many patients.

For more than 33 years, the Society for Immunotherapy of Cancer (SITC) has been the leader in cancer immunotherapy – long before the world would see the impact this treatment modality has made in the fight against cancer. The society’s Annual Meeting & Pre-Conference Programs (SITC 2017) is the largest meeting dedicated solely to the field. This premier conference brings together leading cancer immunotherapy experts from around the world. SITC 2017 promises unparalleled cutting-edge research and networking opportunities. Register today for SITC 2017, scheduled on Nov. 8-12.   You can look forward to five days of state of the science presentations at the SITC annual meeting this fall, where each presentation and poster revolves around cancer immunotherapy.

SITC has always strongly supported the growth and development of young investigators, as the future of cancer immunotherapy is rooted in research and education. Take a look at these opportunities designed to ensure that talented, innovative professionals continue to be attracted to careers in this treatment modality.

Get involved and share these opportunities with a young investigator in your network.
Cancer immunotherapy saves lives and is forever changing what it means to have cancer. Early career scientists provide critical support in the research and innovation in this evolving field.

Thank you for your continued support.


Best wishes,











Lisa H. Butterfield, PhD

SITC President

Thursday, May 25, 2017

President's Message - May 2017

Dear Colleagues,

In recognition of June as Cancer Immunotherapy Month organized by our colleagues at the Cancer Research Institute (CRI), the Society for Immunotherapy of Cancer (SITC) celebrates the numerous advances and positive steps taken in moving the field forward. We applaud all of the researchers, practitioners and advocates who have demonstrated an unwavering devotion to improving outcomes for cancer patients worldwide.

While there is still much work to be done, I invite you to celebrate with SITC in Chicago and join us for events surrounding the ASCO Annual Meeting:
Another event taking place next month is White Out Cancer Day on June 16. We ask those of you who have a SITC Cure t-shirt to take a selfie and tweet at the society (@sitcancer) using the official hashtag #WearWhite or email the photo to communication@sitcancer.org. Show your support on the specific day, or any day during June. If you do not yet own a Cure t-shirt, you can order one here.

As the field continues to grow and expand, a major priority of the society is to support and help develop the next generation of leaders. If you are an early career scientist looking for a unique and amazing new team-based research (and business development) opportunity to help the field, apply now to the SITC Sparkathon. Participants will meet on Aug. 28-29, for a two-day retreat in a “Technology Hackathon” meets “Shark Tank” format to explore the hurdles and challenges facing the field of cancer immunotherapy. Applications are accepted until June 16, so apply soon.

Finally, the society is excited to publish its first textbook, Cancer Immunotherapy Principles and Practice. The SITC textbook, an authoritative reference presenting the history, supporting science and mechanisms as well as the current state of cancer immunotherapy, is now available for pre-order. SITC members are eligible to receive up to a 25 percent discount and free shipping. Login to your SITC CONNECT account for more details including the promo code, or stop by SITC’s exhibit booth #2015 while in Chicago.

Thank you for your continued support of the cancer immunotherapy field.


Best wishes,











Lisa H. Butterfield, PhD

SITC President